Barrett’s Esophagus

What is Barrett’s Esophagus?

Barrett’s esophagus is a condition where the tissue lining the esophagus changes, with the normal squamous cells being replaced by intestinal-type cells. This transformation typically occurs as a result of long-term gastroesophageal reflux disease (GERD).

Key Characteristics

  • Abnormal cell changes in the lower esophagus
  • Salmon-pink appearance of affected tissue
  • Usually affects the lower portion of the esophagus
  • Can develop into precancerous condition

Risk Factors

  • Chronic GERD
  • Age over 50
  • Male gender
  • Obesity
  • Smoking
  • Family history

Common Symptoms

  • Frequent heartburn
  • Difficulty swallowing
  • Chest pain
  • Regurgitation of food
  • Upper abdominal pain

Diagnostic Methods

  • Upper endoscopy
  • Tissue biopsy
  • pH monitoring
  • Imaging studies

Treatment Approaches

  1. Medications:   
  • Proton pump inhibitors
  • H2 blockers
  • Antacids
  1. Endoscopic treatments:   
  • Radiofrequency ablation
  • Endoscopic mucosal resection
  • Cryotherapy
  1. Surgery in severe cases

Prevention and Management

  • Regular monitoring through endoscopy
  • Lifestyle modifications:   
  • Weight management
  • Avoiding trigger foods
  • Eating smaller meals
  • Not lying down after eating
  • Smoking cessation
  • Maintaining a healthy weight

Blood in stools / vomitus